Susceptibility of periodontitis and its impact on patients with inflammatory bowel disease

Authors

  • Ayman M. Albalbisi North Jeddah Specialized Dental Center, King Abdullah Medical Complex, Jeddah, Saudi Arabia
  • Saad A. Alshamrani Department of Dentistry, Eastern Riyadh Dental Center, Riyadh, Saudi Arabia
  • Mohammed J. Al Bu Eid Department of Health Education, Eastern Riyadh Dental Center, Riyadh, Saudi Arabia
  • Mesfer S. Alalyani North Riyadh Dental Center, Second Health Cluster Central Region, Riyadh, Saudi Arabia
  • Najat R. Al-Mousa Department of General Dentistry, Dental Medical Complex in West of Riyadh, Riyadh, Saudi Arabia
  • Mamdouh A. Alshammari Department of General Dentistry, Huraymala General Hospital, Riyadh, Saudi Arabia
  • Ali S. Alqahtani Department of Dentistry, Eastern Riyadh Dental Center, Riyadh, Saudi Arabia
  • Amjad M. Alqahtani Department of Dentistry, Eastern Riyadh Dental Center, Riyadh, Saudi Arabia
  • Abdulrahman M. Alqahtani Department of Dentistry, Eastern Riyadh Dental Center, Riyadh, Saudi Arabia
  • Saud A. Alqahtani Department of General Dentistry, Dental Medical Complex in West of Riyadh, Riyadh, Saudi Arabia
  • Mohammad A. Hilmi North Jeddah Specialized Dental Center, King Abdullah Medical Complex, Jeddah, Saudi Arabia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20223236

Keywords:

Periodontitis disease, Inflammatory bowel disease, Ulcerative colitis, Crohn’s disease

Abstract

Inflammatory bowel disease (IBD) and periodontitis are chronic, progressive, inflammatory diseases with similarly complex pathogeneses that include dysbiotic microbiota and dysregulated immune-inflammatory responses, and both are influenced by genetic and environmental factors. This review aimed to provide an overview of the emerging evidence dealing with the susceptibility of periodontal disease and its impacts on patients with IBD by explaining the risk factors, possible pathogenic interactions, and disease activity by reviewing recent literature from open-source journals on the same topic. There seems to be an increased prevalence of periodontitis in patients with IBD when compared to healthy controls, which was more pronounced in ulcerative colitis (UC) than Crohn’s disease (CD). In addition, both greater severity and extent of periodontitis have been found in IBD patients when compared to healthy controls. Age, gender, lifestyle or environmental factors, and smoking history were the associated risk factors. In conclusion, the findings suggest that patients with IBD be kept under close surveillance to prevent periodontitis and/or mitigate its progression. Oral health education and effective treatment are required for IBD patients. However, we still need more data derived from human studies to confirm the results. Thus, mechanistic studies are warranted to clarify this possible bidirectional association.

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Published

2022-11-28

How to Cite

Albalbisi, A. M., Alshamrani, S. A., Al Bu Eid, M. J., Alalyani, M. S., Al-Mousa, N. R., Alshammari, M. A., Alqahtani, A. S., Alqahtani, A. M., Alqahtani, A. M., Alqahtani, S. A., & Hilmi, M. A. (2022). Susceptibility of periodontitis and its impact on patients with inflammatory bowel disease. International Journal Of Community Medicine And Public Health, 9(12), 4715–4719. https://doi.org/10.18203/2394-6040.ijcmph20223236

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Section

Review Articles