A study of leprosy patients attended tertiary care hospital

Yugantara R. Kadam, Renuka S. Ashtekar, Vishrabdha R. Pawar, Aniruddha N. Pimpale


Background: Recorded leprosy case load has come down from to less than one case per 10,000 populations at national level in December 2005. Considerable changes in the epidemiological pattern of the disease have been observed due to the historical trend of the disease; the impact of interventions; the efficacy of chemotherapy and the role of improved health services. This study was planned to know the pattern of leprosy cases attending tertiary care hospital, their treatment & outcome.

Methods: It is a retrospective study conducted from Bharati Vidyapeeth Deemed University Medical College & Hospital from 2007 till December 2015.   Study-subjects include patients with leprosy and sample size includes all the patients of leprosy from January 2007 to December 2015. The study-tools: records, biopsy tissue blocks. Statistical analysis: percentages.

Results: There were total 42 cases. Total 9.5% were children. Male to female ratio was 1.33:1. Two (4.8%) patients gave family history of leprosy, 23 (54.8%) were from rural area. Clinically 16.66% patients had single patch, 50% had nerve involvement. The most common type was borderline tuberculoid leprosy (35.7%). Out of these 42 cases 22 cases had completed the treatment, 14 on treatment. Six patients were defaulted.

Conclusions: Early diagnosis & treatment of leprosy is happening as none of the cases had disability. History of contact in study subject was not common & presence of leprosy in paediatric age group indicates continued transmission. However there is a need of strong follow-up system for defaulters.


Clinical pattern of leprosy, Histopathological pattern of leprosy, Leprosy, Paediatric leprosy

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Park K. Park’s Textbook of Preventive & Social Medicine. Leprosy. Ms. Banarasidas Bhanot Publishers; 22nd Edition. 2013: 287-302.

Jindal N, Shanker V, Tegta GR, Gupta M, Verma GK. Clinico-epidemiological Trends of Leprosy in Himachal Pradesh: A Five Year Study. Indian J Lepr. 2009;81:173-9.

World Health Organization, Leprosy Elimination Monitoring (LEM).Guidelines for monitors 2000.

Giridhar M, Arora G, Lajpal K, Chahal K.S. Clinicohistopathological concordance in leprosy: A clinical, histopathological & bacteriological study of 100 cases. Indian J Lepr. 2012;84:217-25.

Singh A, Gaur R, Ambey R. Spectrum of leprosy patients with clinic-histopathological correlation: A hospital based study. Asian J Med Sci. 2013;4(4):11-6.

Suri SK, Iyer RR, Patel DU, Bandil S, Baxi S. Histopathology & clinicohistopathological correlation in Hansen’s Disease. J Res Med Dental Sci. 2014;2(1):37-43.

Vora RV, Diwan NG, Patel NH, Singhal RR, Ashok P. Clinico-histopathological correlation in leprosy: A study at a rural based tertiary care centre, Gujrat. Indian J Clinical & Experimental Dermatology. 2016;2(1):23-6.

Rizvi AA, Sharma YK, Dash K, Tyagi N, Yadava R, Sadana D. An epidemiological and clinic-histopathological study of leprosy in semi-urban area under Pimpari Chinchwad Municipal Corporation in Pune district of Maharashtra. Med J Dr. D. Y. Patil University. 2015;8(5):609-13.

Singh I, Lavania M, Nigam A, Ravindra P, Turank A.R, Ahuja M, John A.S, Sengupta U. Symposium on emerging needs in leprosy research in the post elimination era: The Leprosy Mission Trust India.Lepr Rev. 2016;87:132-43.

Parekh R, Mulchndani V, Parakh KK. Clinico-histopathological correlation in leprosy: A tertiary care hospital based study at Udaypur. IJSR. 2015;4(10):56-8.

Niang SO, Diallo M, Ndiaye M, Diop A, Diatta B.A, Wadih M, Kane A, Dieng MT, Badiane CI. Epidemiological & clinicopathologic aspects of leprosy in Dakar; evaluation of 73 new cases. Dermatology Reports. 2011:3(e18):40-2.

Golfurushan F, Sadeghi M, Goldust M, Yosefi N. Leprosy in Iran: an analysis of 195 cases from 1994-2009. JPMA. 2011:61(6):558-60.

Chaitra P, Bhat RM. Postelimination status of childhood leprosy: Report from a tertiary care hospital in South India. BioMed Research International 2013. 10.1155/2013/328673

Khan I, Khan AR, Khan MS. Clinicopathological study of 50 cases of leprosy in Northern Pakistan. J Pakistan Association Dermatologistsn. 2012;22(3):200-6.

Lucas S. Bacterial diseases In: David E Elder. Lever’s histopathology of skin. 9th ed. Phyladelphia, Lipincott Williams & Wilkins. 2005: 551-90.

Naves MM, Patrocinio LG, Patrocinio JA, Mota FMN, De Souza AD, Fleury RN, Goulart IMB. Contribution of nasal biopsy to leprosy diagnosis. Am J Rhinolo Aller. 2009:23;177-80.