Role of statins in primary prevention of cardiovascular disease

Authors

  • Hamed S. Al Ghamdi Department of Internal Medicine, King Abdulaziz Hospital, Jeddah, Saudi Arabia
  • Khalaf M. Alkhalaf Emergency Medical Services, King Salman Hospital, Riyadh, Saudi Arabia
  • Ahmad S. AlJafen General Physician, Buraidah Central Hospital, Buraidah, Saudi Arabia
  • Mutlaq G. Alotaibi Primary Health Care, King Fahad Specialist Hospital, Buraidah, Saudi Arabia
  • Mohammed M. Algudaihi College of Medicine, Medical University of Białystok, Białystok, Poland
  • Basmah H. Alhawiti Department of Internal Medicine, King Khalid Hospital, Tabuk, Saudi Arabia
  • Fatima F. Al Hamad General Physician, Al-Omran General Hospital, Al-Ahsa, Saudi Arabia
  • Abdullah A. Alessa General Physician, King Salman Armed Forces Hospital, Tabuk, Saudi Arabia
  • Ghofran B. Al Saif General Physician, Abqaiq General Hospital, Abqaiq, Saudi Arabia
  • Bader T. Alshammari Department of Internal Medicine, Aladan Hospital, Al-Adan, Kuwait
  • Saadiah A. Balkhy Department of Internal Medicine, Security Forces Hospital, Mecca, Saudi Arabia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20222365

Keywords:

Statin, Primary, Prevention, Cardiovascular, Disease

Abstract

Cardiovascular disease continues to remain a global health challenge due to its increasing trend of prevalence. Almost, 6.2 million deaths were caused by cardiovascular diseases among patients of age range 30-70 years in 2019. The burden of cardiovascular diseases can only be reduced by implementation of effective preventive strategies. Primary prevention is of utmost importance since individuals at risk are treated beforehand thus reducing the chance of development of disease. Statins are lipid lowering agents and are used in primary prevention of cardiovascular disease. The purpose of this research is to review the available information about role of statins in primary prevention of cardiovascular disease. Generally, statins are considered as safe and effective medications to treat and reduce the morbidity of cardiovascular diseases. The relative risk of coronary events, cardiovascular disease mortality, non-fatal strokes, and all-cause mortality is decreased with statin therapy. Elderly population or individuals at risk of development of cardiovascular diseases can be efficiently managed by statin therapy. Some studies associate the occurrence of diabetes with the use of statins but most of the studies recommend the role of statins in prevention as benefits outweigh the risks. Literature also supports the role of statins in primary prevention although more clinical studies in future can yield better evidence-based results to support the use of statins especially in primary prevention.

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Published

2022-09-28

How to Cite

Al Ghamdi, H. S., Alkhalaf, K. M., AlJafen, A. S., Alotaibi, M. G., Algudaihi, M. M., Alhawiti, B. H., Al Hamad, F. F., Alessa, A. A., Saif, G. B. A., Alshammari, B. T., & Balkhy, S. A. (2022). Role of statins in primary prevention of cardiovascular disease. International Journal Of Community Medicine And Public Health, 9(10), 3873–3877. https://doi.org/10.18203/2394-6040.ijcmph20222365

Issue

Section

Review Articles