Efficacy of multi-powered continuous positive airway pressure device on neonates bearing respiratory distress syndrome: an observational analytical study

Authors

  • Jagadeesh . Department of Paediatrics, M. V. J. Medical College and Research Hospital, Hoskote, Karnataka, India http://orcid.org/0000-0001-5644-6579
  • Bhavana M. S. Clinical Research Specialist, Public Health Consultant in Bangalore, Karnataka, India
  • Megha Singh Clinical Research Specialist, Public Health Consultant in Bangalore, Karnataka, India
  • Kavitha . Department of Paediatrics, M. V. J. Medical College and Research Hospital, Hoskote, Karnataka, India
  • Ravi Chander Department of Paediatrics, M. V. J. Medical College and Research Hospital, Hoskote, Karnataka, India

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20215004

Keywords:

Continuous positive airway pressure therapy, Mechanical ventilation, Respiratory distress syndrome

Abstract

Background: CPAP (continuous positive airway pressure), an effective intervention for respiratory distress in neonates. Following the development of simple, safe and relatively inexpensive CPAP devices. Saans (CPAP device) is one such portable, easy to use device which is operable in low resource settings, can be used as T-piece resuscitator in the delivery room and during transport. The aim of this study was to evaluate the efficacy of a low cost, multi-powered and easy to use CPAP device Saans, developed by Coeo Labs Pvt. Ltd., Bangalore, on neonates with respiratory distress.

Methods: An observational analytical study per the protocol, 35 neonates gestational age >30 weeks were enrolled. Primary outcome variable was the need for mechanical ventilation. Secondary outcome variables were the rate of survival, duration of oxygen in hours, duration of ventilation in hours, duration of hospital stay in days, change Downe score, SAS score, heart rate, respiratory rate and FiO2 from enrolment 6 hours of intervention.

Results: 89% (31 neonates) enrolled with respiratory distress. 11% (4 neonates) failed to improve on CPAP therapy. A significant decline in the need for FiO2, mean Downe score, mean R and heart rate observed from the baseline 6 hours CPAP (p<0.001), t test analysis, factors significantly associated CPAP failure were high FiO2 at 1 hour and high positive end-expiratory pressure within 1 hour initiating CPAP (p<0.001).

Conclusions: Saans (CPAP device), successful therapeutic option for neonates with respiratory distress and can be effective even in a resource-constrained clinical setting.

Author Biography

Jagadeesh ., Department of Paediatrics, M. V. J. Medical College and Research Hospital, Hoskote, Karnataka, India

Clinical Research Associate

Public Health Professional

References

Morley CJ. Surfactant. Curr Obstet Gynaecol. 1996;6(1):46-51.

Singh SN, Mundada S. Efficacy of indigenous bubble CPAP in treating respiratory distress of newborn. Int J Gynaecol. 2017;4(1):14-6.

Thaddanee R, Chaudhari A, Chauhan H. Bubble continuous positive airway pressure machine versus indigenous bubble continuous positive airway pressure as a respiratory support in preterm babies with respiratory distress. Int J Contemp Pediatr. 2018;5(2):493-8.

Kawaza K, Machen HE, Brown J, Mwanza Z, Iniguez S, Gest A, et al. Efficacy of a low-cost bubble CPAP system in treatment of respiratory distress in a neonatal ward in Malawi. PLoS One. 2014;9(1):1-8.

Diblasi RM. Nasal continuous positive airway pressure (CPAP) for the respiratory care of the newborn infant. Respir Care. 2009;54(9):1209-35.

Koyamaibole L, Kado J, Qovu J, Colquhoun S, Duke T. An evaluation of bubble-CPAP in a neonatal unit in a developing country: effective respiratory support that can be applied by nurses. J Trop Pediatr. 2006;52(4):249-53.

Tagare A, Kadam S, Vaidya U, Pandit A, Patole S. A pilot study of comparison of BCPAP vs. VCPAP in preterm infants with early onset respiratory distress. J Trop Pediatr. 2010;56(3):191-4.

Pieper C, Smith J, Maree D, Pohl F. Is nCPAP of value in extreme preterms with no access to neonatal intensive care? J Trop Pediatr. 2003;49(3):148-52.

Caroline C, Coulborn C, Heys M, Molyneux MU. Evaluation of ‘TRY’: an algorithm for neonatal continuous positive airways pressure in low-income settings. Arch Dis Childhood. 2017.

Ballot DE, Chirwa TF, Cooper PA. Determinants of survival in very low birth weight neonates in a public sector hospital in Johannesburg. BMC Pediatr. 2010;10:30.

Pieper CH, Smith J, Maree D, et al. Is nCPAP of value in extreme preterms with no access to neonatal intensive care? J Trop Pediatr. 2003;49(3):148-52.

Kawaza K, Machen HE, Brown J, et al. Efficacy of a low-cost bubble CPAP system in treatment of respiratory distress in a neonatal ward in Malawi. PLoS One. 2014;9(1):86327

Downloads

Published

2021-12-27

How to Cite

., J., M. S., B., Singh, M., ., K., & Chander, R. (2021). Efficacy of multi-powered continuous positive airway pressure device on neonates bearing respiratory distress syndrome: an observational analytical study. International Journal Of Community Medicine And Public Health, 9(1), 240–245. https://doi.org/10.18203/2394-6040.ijcmph20215004

Issue

Section

Original Research Articles