Community perception and determinants of willingness to uptake COVID-19 vaccines among residents of Osun State, South-West Nigeria

Patrick A. Akinyemi, Olusola Fajobi, Israel A. Owoade, Olanrewaju T. Elugbaju, Funmilola O. Wuraola


Background: Vaccine has been identified as the most cost-effective way of fighting COVID-19 pandemic. As most countries await the COVID-19 vaccine for mass administration amidst numerous misconceptions, it is imperative to assess willingness of the masses to take the vaccine. This study aimed to assess the determinants of willingness to uptake COVID-19 vaccines among residents of Osun State.

Methods: A descriptive cross-sectional study design was employed. Seven hundred and forty-four respondents were enrolled from three selected local government areas using a multistage sampling method. Interviewer administered questionnaire, structured based on the health belief model and social cognitive theory, in electronic format (Kobo Collect) was used for data collection. Determinants of willingness to take COVID-19 vaccine were assessed using binary logistic regression.

Results: About three-quarters (59.1%) of the respondents were willing to take the vaccine. There was a significant association between positive perception and willingness to take COVID-19 vaccine, p<0.001. Being a healthcare worker, having good knowledge of the disease, and willingness-to-pay for the vaccine were significant determinants of willingness to uptake COVID-19 vaccine. Presence of misconception had a negative effect on the uptake of COVID-19 vaccine.

Conclusions: To achieve high COVID-19 vaccine coverage, there is a need for health promotion interventions to correct misconceptions about COVID-19. Government and private donor interventions may be required to subsidize the vaccine to care for the populace who are willing to uptake but unable to pay for the vaccine.


Community perception, COVID-19, Osun State, Vaccine, Willingness-to-uptake

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WHO. COVID-19 Public Health Emergency of International Concern (PHEIC) Global research and innovation forum. 2020; publications/m/item/covid-19-public-health-emergency-of-international-concern-(pheic)-global-research-and-innovation-forum.

National Institute of Health. Clinical Trial For SARS-CoV-2 Vaccine (COVID-19). 2020;

Polack FP, Thomas SJ, Kitchin N. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine. New England J Medic. 2020;383(27):2603-15.

Pan American Health Organization. Presentation: Infection Prevention and Control and novel coronavirus (COVID-19): standard precautions and use of personal protective equipment. 2020;

WHO. Managing the COVID-19 infodemic: Promoting healthy behaviours and mitigating the harm from misinformation and disinformation. 2020;

Ahmed W, Vidal-Alaball J, Downing J, López Seguí F. COVID-19 and the 5G Conspiracy Theory: Social Network Analysis of Twitter Data. J Med Internet Res. 2020;22(5):e19458.

Meese J, Frith J, Wilken R. COVID-19, 5G conspiracies and infrastructural futures. Media International Australia. 2020:1329878X20952165.

World Health Organisation. Health Education: Theoretical Concepts, Effectiveness Strategies and Core Competencies. Cairo, Egypt: World Health Organisation; 2012.

World Bank. Poverty and Equity Data Portal. 2019;

Padhi BK, Al-Mohaithef M. Determinants of COVID-19 vaccine acceptance in Saudi Arabia: a web-based national survey. medRxiv. 2020.

Sherman SM, Smith LE, Sim J. COVID-19 vaccination intention in the UK: results from the COVID-19 vaccination acceptability study (CoVAccS), a nationally representative cross-sectional survey. Human Vaccines & Immunotherapeutics. 2020:1-10.

Lazarus JV, Ratzan SC, Palayew A, et al. A global survey of potential acceptance of a COVID-19 vaccine. Nature Medicine. 2020.

Paul E, Steptoe A, Fancourt D. Attitudes towards vaccines and intention to vaccinate against COVID-19: Implications for public health communications. The Lancet Regional Health - Europe. 2020.

Gagneux-Brunon A, Detoc M, Bruel S. Intention to get vaccinations against COVID-19 in French healthcare workers during the first pandemic wave: a cross-sectional survey. J Hospital Infec. 2021;108:168-73.

Harapan H, Wagner AL, Yufika A. Acceptance of a COVID-19 Vaccine in Southeast Asia: A Cross-Sectional Study in Indonesia. Front Public Health. 2020;8:381.

Detoc M, Bruel S, Frappe P, Tardy B, Botelho-Nevers E, Gagneux-Brunon A. Intention to participate in a COVID-19 vaccine clinical trial and to get vaccinated against COVID-19 in France during the pandemic. Vaccine. 2020;38(45):7002-6.

Al-Mohaithef M, Padhi BK. Determinants of COVID-19 Vaccine Acceptance in Saudi Arabia: A Web-Based National Survey. J Multidiscip Healthc. 2020;13:1657-63.

Dodd RH, Cvejic E, Bonner C, Pickles K, McCaffery KJ, Sydney Health Literacy Lab C-g. Willingness to vaccinate against COVID-19 in Australia. Lancet Infect Dis. 2020.

Goldman RD, Staubli G, Cotanda CP. Factors associated with parents’ willingness to enroll their children in trials for COVID-19 vaccination. Human Vaccines & Immunotherapeutics. 2020:1-5.

Abu-Farha RK, Alzoubi KH, Khabour OF. Public Willingness to Participate in COVID-19 Vaccine Clinical Trials: A Study from Jordan. Patient Prefer Adherence. 2020;14:2451-8.

Reiter PL, Pennell ML, Katz ML. Acceptability of a COVID-19 vaccine among adults in the United States: How many people would get vaccinated? Vaccine. 2020;38(42):6500-7.

Lin Y, Hu Z, Zhao Q, Alias H, Danaee M, Wong LP. Understanding COVID-19 vaccine demand and hesitancy: A nationwide online survey in China. PLOS Neglected Tropical Diseases. 2020;14(12):e0008961.

Shmueli L. Predicting intention to receive COVID-19 vaccine among the general population using the Health Belief Model and the Theory of Planned Behavior Model. medRxiv. 2020.

Tam CC, Qiao S, Li X. Factors associated with decision making on COVID-19 vaccine acceptance among college students in South Carolina. medRxiv. 2020.