Risk factors for bronchial asthma among children in Medina city, Saudi Arabia: an ecological approach

Authors

  • Alaa Alahmadi Department of Public Health, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
  • Hoda Jradi Department of Public Health, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia
  • Eyad Alofi College of Medicine, Taibah University, Ministry of Education, Medina, Saudi Arabia

DOI:

https://doi.org/10.18203/2394-6040.ijcmph20204360

Keywords:

Bronchial asthma, Ecological model, Saudi Arabia, Risk factors, Children

Abstract

Background: Asthma is a common disease in Saudi Arabia that affects many individuals. Children are profoundly affected, and the impact of the disease is noticeable in the frequent visits to the emergency departments, missed school days, recurrent hospitalizations, and high death rates. Our study is aimed at identifying the determinant of bronchial asthma risk factors based on the ecological model.

Methods: A case-control study was conducted. Samples were randomly selected from two major hospitals in Medina Region, Saudi Arabia, including children aged between 1-14 years. A chi-square test was used to see any differences across categories between cases and control. Significant factors associated with asthma in bivariate analysis were submitted to conditional multivariate logistic regression analysis.

Results: Factors significantly associated with asthma were being obese (OR=5.10; 95% CI 2.09-12.42), having a history of allergic rhinitis (OR=7.10; 95% CI 3.24-15.52), born preterm (OR=6.06; 95% CI 2.05-17.87), living in a carpeted home (OR=3.06; 95% CI 1.41-6.64), using a gas stove (OR=9.09; 95% CI 3.93-21.03), playing with plush toys (OR=4.58; 95% CI 2.04-10.30), living in a home distanced less than 500 meters from the main traffic road (OR=3.68; 95% CI 1.27-10.70), less than 500 meters from a plant farm (OR=3.78; 95% CI 1.68-10.70), and less than 500 meters from an electric station (OR=5.57; 95% CI 1.73-17.93).

Conclusions: This study confirms the associations between individual, outdoor-indoor environmental factors, and bronchial asthma among children in Medina. This study is a step forward into the future of interventional programs to control bronchial asthma among children.

Metrics

Metrics Loading ...

References

Alahmadi TS, Banjari MA, Alharbi AS. The prevalence of childhood asthma in Saudi Arabia. Int J Pediatr Adolescent Med. 2019;6(2):74.

Anderson H, Butland B, Strachan D. Trends in prevalence and severity of childhood asthma. BMJ. 1994;308(6944):1600-4.

Galassi C, De Sario M, Biggeri A, Bisanti L, Chellini E, Ciccone G, et al. Changes in prevalence of asthma and allergies among children and adolescents in Italy: 1994-2002. Pediatrics. 2006;117(1):34-42.

Roslan MS, Johari MM, Mubing NA, Fadzilah HH. Sociodemographic profile of childhood asthma among children in Selangor-Malaysia. Pediatric Research. 2011;70(S5):557.

Lin W, Huang W, Zhu T, Hu M, Brunekreef B, Zhang Y, et al. Acute respiratory inflammation in children and black carbon in ambient air before and during the 2008 Beijing Olympics. Environmental health perspectives. 2011;119(10):1507-12.

Mirzaei M, Karimi M, Beheshti S, Mohammadi M. Prevalence of asthma among Middle Eastern children: A systematic review. Med J Islamic Republic Iran. 2017;31:9.

Al Thamiri D, Al Kubaisy W, Ali S. Asthma prevalence and severity among primary-school children in Baghdad. EMHJ. 2005;11(1-2):79-86.

Ones U, Akcay A, Tamay Z, Guler N, Zencir M. Rising trend of asthma prevalence among Turkish schoolchildren (ISAAC phases I and III). Allergy. 2006;61(12):1448-53.

Al-Moamary MS, Alhaider SA, Alangari AA, Al Ghobain MO, Zeitouni MO, Idrees MM, et al. The Saudi Initiative for Asthma-2019 Update: Guidelines for the diagnosis and management of asthma in adults and children. Ann Thorac Med. 2019;14(1):3.

Alsulaimani A, Awad NS, El-Tarras AE. Genetic basis of childhood asthma in Saudi Arabia. Int J Curr Microbiol App Sci. 2015;4(6):317-25.

Kuiper S, Muris JW, Dompeling E, Kester AD, Wesseling G, Knottnerus JA, et al. Interactive effect of family history and environmental factors on respiratory tract-related morbidity in infancy. J Aller Clin Immunol. 2007;120(2):388-95.

DiFranza JR, Aligne CA, Weitzman M. Prenatal and postnatal environmental tobacco smoke exposure and children's health. Pediatrics. 2004;113(3):1007-15.

Subbarao P, Mandhane PJ, Sears MR. Asthma: epidemiology, etiology, and risk factors. CMAJ. 2009;181(9):181-90.

Alqahtani JM, Asaad AM, Awadalla NJ, Mahfouz AA. Environmental determinants of bronchial asthma among Saudi school children in Southwestern Saudi Arabia. Int J Environ Res Public Health. 2017;14(1):22.

Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet. 2012;380(9859):2224-60.

Lee Y-L, Lin Y-C, Hsiue T-R, Hwang B-F, Guo YL. Indoor and outdoor environmental exposures, parental atopy, and physician-diagnosed asthma in Taiwanese schoolchildren. Pediatrics. 2003;112(5):389

Idris IB, Ghazi HF, Zhie KH, Khairuman KA, Yahya SK, Zaim FAA, et al. Environmental air pollutants as risk factors for asthma among children seen in pediatric clinics in UKMMC, Kuala Lumpur. Ann Global Health. 2016;82(1):202-8.

Findley S, Lawler K, Bindra M, Maggio L, Penachio MM, Maylahn C. Elevated asthma and indoor environmental exposures among Puerto Rican children of East Harlem. J Asthma. 2003;40(5):557-69.

Harju T, Keistinen T, Tuuponen T, Kivelä SL. Seasonal variation in childhood asthma hospitalisations in Finland, 1972-1992. European journal of pediatrics. 1997;156(6):436-9.

Khreis H, Kelly C, Tate J, Parslow R, Lucas K, Nieuwenhuijsen M. Exposure to traffic-related air pollution and risk of development of childhood asthma: a systematic review and meta-analysis. Env Int. 2017;100:1-31.

Weinmayr G, Forastiere F, Büchele G, Jaensch A, Strachan DP, Nagel G, et al. Overweight/obesity and respiratory and allergic disease in children: international study of asthma and allergies in childhood (ISAAC) phase two. PloS one. 2014;9(12):e113996.

Mebrahtu TF, Feltbower RG, Greenwood DC, Parslow RC. Childhood body mass index and wheezing disorders: a systematic review and meta‐analysis. Pediatric Allergy Immunol. 2015;26(1):62-72.

Granell R, Henderson AJ, Evans DM, Smith GD, Ness AR, Lewis S, et al. Effects of BMI, fat mass, and lean mass on asthma in childhood: a Mendelian randomization study. PLoS medicine. 2014;11(7):e1001669.

He H, Butz A, Keet CA, Minkovitz CS, Hong X, Caruso DM, et al. Preterm birth with childhood asthma: the role of degree of prematurity and asthma definitions. Am J Respirator Critical Care Med. 2015;192(4):520-3.

Al-Mazam A, Mohamed AG. Risk factors of bronchial asthma in Bahrah, Saudi Arabia. J Fam Comm Med. 2001;8(1):33.

Corren J. Allergic rhinitis and asthma: how important is the link? J Allergy Clin Immunol. 1997;99(2):781-6.

Lundbäck B. Epidemiology of rhinitis and asthma. Clinical and experimental allergy: J Br Society Allergy Clin Immunol. 1998;28:3-10.

Kanchongkittiphon W, Mendell MJ, Gaffin JM, Wang G, Phipatanakul W. Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine. Environmental health perspectives. 2014;123(1):6-20.

Paulin LM, Diette GB, Scott M, McCormack MC, Matsui EC, Curtin‐Brosnan J, et al. Home interventions are effective at decreasing indoor nitrogen dioxide concentrations. Indoor Air. 2014;24(4):416-24.

Azalim SP, Camargos P, Alves AL, Senna MIB, Sakurai E, Schwabe Keller W. Exposure to environmental factors and relationship to allergic rhinitis and/or asthma. Ann Agricultural Env Med. 2014;21(1).

Teo KS, Cheah CW, Mak JW. Association between house dust mite (HDM) sensitisation and asthma control using skin prick test and HDM antigen specific IgE levels in saliva of Malaysian children. Int J Sci Med Educ. 2015;9:3-12.

Corlin L, Woodin M, Newhide D, Brown E, Diaz S, Chi A, et al. Asthma associations in children attending a museum of science. Int J Environ Res Public Health. 2013;10(9):4117-31.

Kasznia-Kocot J, Kowalska M, Górny RL, Niesler A, Wypych-Slusarska A. Environmental risk factors for respiratory symptoms and childhood asthma. Ann Agricultural Environ Med. 2010;17(2):221-9.

Kogevinas M, Antó JM, Sunyer J, Tobias A, Kromhout H, Burney P, et al. Occupational asthma in Europe and other industrialised areas: a population-based study. The Lancet. 1999;353(9166):1750-4.

Naleway AL. Asthma and atopy in rural children: is farming protective? Clin Medicine Res. 2004;2(1):5-12.

Amster E, Lew Levy C. Impact of coal-fired power plant emissions on children's health: a systematic review of the epidemiological literature. Int J Environ Res Public Health. 2019;16(11):2008.

Hao J, Wang L, Shen M, Li L, Hu J. Air quality impacts of power plant emissions in Beijing. Environmental Pollution. 2007;147(2):401-8.

Guarnieri M, Balmes JR. Outdoor air pollution and asthma. The Lancet. 2014;383(9928):1581-92..

Downloads

Published

2020-09-25

How to Cite

Alahmadi, A., Jradi, H., & Alofi, E. (2020). Risk factors for bronchial asthma among children in Medina city, Saudi Arabia: an ecological approach. International Journal Of Community Medicine And Public Health, 7(10), 3952–3962. https://doi.org/10.18203/2394-6040.ijcmph20204360

Issue

Section

Original Research Articles