The effect of Aloe vera compress on the plebitis degrees due to intravena therapy in children

Veolina Irman, Fenny Fernando


Background: Intravenous therapy is a kind of therapy which is often given to children patients. The use of intravenous in a long time will cause phlebitis. Non pharmacology action to cure phlebitis is by applying aloe vera compress on it. Aloe vera is useful because it has low electrolyte concentrate, so it will not cause extravation. This research aims to learn the effect of giving aloe vera to phlebitis children.

Methods: The research method is using Quasi experiment with randomized control group pre-test and post-test design. The sample of the research is 30 phlebitis children who are taken randomly. The sample is divided into two groups; 15 phlebitis children are cured with aloe vera compress, and the other 15 are cured by using pure aloe vera. The treatment is done 3 times a day for two days. Phlebitis degree is measured by using phlebitis scale infusion nurse society (INS) before and after interruption.

Results: his research finds that the average degree before the act is 3 with minimum-maximum score 1-4. The degree of phlebitis after the act becomes 2 with minimum-maximum score 1-3. Aloe Vera is effective for lowering the degree of children phlebitis with p=0.0000. The test used Mann-Whitney.

Conclusions: Aloe vera compress is effective in reducing the degree of phlebitis.


Aloe vera, Intravena, Plebitis

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Zheng GH, Yang L, Chen HY, Chu JF, Mei L. Aloe vera for prevention and treatment of infusion phlebitis. Cochrane Database Syst Rev. 2014;3:23-35.

Lavery I, Ingram P. Safe practice in intravenous medicines administration. Nursing Stand. 2008;4(6):44-7.

Alexander M, Corrigan A, Gorskin L, Hankins J, Perucca R. Infusion nursing: An evidence-based approach. Missouri: Saunder Elsev. 2010;2(1):12-5.

Foster L, Wallis M, Paterson B, James H. A descriptive study of peripheral intravenous catheters in patients admitted to a pediatric unit in one Australian hospital. J Infus Nurs. 2002;25(3):159-67.

Prestji R. French Medical Institute for Children (FMIC): A study on incidences of phlebitis and causes in pediatric patients at FMIC, Afghanistan. 2007;2(1):45-9.

Ray-Barruel G, Polit DF, Murfield JE, Rikard CM. Infection phlebitis assessment measures: A systematic review. J Eval Clin Pract. 2014;2(1):191-202.

Zheng GH, Yang L, Chen HY, Chu JF, Mei L. Aloe vera for prevention and treatment of infusion phlebitis. Cochrane Database Syst Reviews. 2014(6).

Suzanna JD, D 'Souuza SW, Malarvizhi M. Effectiveness of fresh aloe vera and glycerine magnesium sulphate: Application on phlebitis among children. Int J Curr Res. 2014;4(2):12-6.

Infusion nursing Society INS. J Infusion Nurs. 2010;34(1S):1–10.

Pharmaceutical, Preventing and Treating Gout. Yogyakarta: Araska; 2008: 45-49.

The Centers for Disease Control and Prevention; 2002: 56-58.

Arifin J. Intensive aloe vera cultivation with increasing prospects, Yogyakarta: New Library Press; 2015: 1-25.

Candra D, Anita K, Prihatinningsih D. Effectiveness of aloe vera juice on blood sugar in diabetic patients. J Nurs Midwifery Stikes Asyah Jogjakarta High School Health Sci. 2009;3(1):2-7.

Djubaedah E. Processing aloe vera in syrup. Pre-forum appreciation and commercialization of research results. Center Agro Industry, Bogor. 2003;3(5):25-7.

Purbaya JR. Knowing and utilizing the efficacy of aloe vera (Aloe Vera). Bandung; 2003: 36-39.

Duke R. Plant contituents are biologycal effect database: chemical and their biological activists in aloe veral. Am J Physiol - Endocrinol Metabol. 2002;4(2):913-21.

McCarthy AM, Kleiber C, Hanrahan K, Zimmerman MB, Westhus N, Allen. Factors explaining children’s responses to intravenous needle insertions. Nurs Res. 2010;59(6):407-16.

Jacinto AKL, Avelar AFM, Wilson AMMM, Pedreira MLG. Phlebitis associated with peripheral intravenous catheters in children: Study of predisposing factors. Escola Anna Nery. 2014:18(2):220-6.

Pearch J. Restraining children for clinical procedures: In contrast to staff in educational settings, child health professionals are not receiving adequate training for holding and restraining children. Jo Pearch explores the issues. Paediatr Nurs. 2005;17(9):36-8.

Abdul-Hak CK, Barros ÂF. The incidence of phlebitis in a Medical Clinical Unit. Texto Contexto – Enfermagem. 2014;23(3):633-8.

Nagpal P, Khera GK, Kumar Y. A study assesses the clinical pattern of phlebitis among children admitted in selected hospital of Ambala, Haryana. Nurs Midwifery Res J. 2015;11(2):68-77.

Oswati. Reducing the degree of phlebitis due to intravenous therapy in children with aloe Vera compress: a pilot study. Indonesian J Nurs. 2017;20(1):1-8.

Kohno E, Murase S, Matsuyama K, Okamura N. Effect of corticosteroids onflebitis induced by intravenous infusion of antineoplastic agents in rabbits. Int J Med Sci. 2009;6(4):218-23.

Phlebitis MD. A painful complication of peripheral IV catheterization that may be prevented. Am J Nurs. 2003;103(2):55-60.

Uslusoy E, Mete S. Predisposing factors to phlebitis in patients with peripheral intravenous catheter: A descriptive study. J Am Acad Nurse Pract. 2008;20(4):172-80.

Lee YS, Ju HK, Kim YJ, Lim TG, Uddin MR, Kim YB, et al. Enhancement of anti-inflammatory activity of Aloe vera adventitious root extracts through the alteration of primary and secondary metabolites via salicylic acid elicitation. PloS One. 2003;8(12):24-79.

Malik I, Zarnigar HN. Aloe vera: a review of its clinical effectiveness. Int Res J Pharma. 2013;4(8):75-9.