A study on prevalence of chronic kidney disease and its risk factors among adults in selected slums of Chennai
Keywords:CKD, Adults, Slum, Diabetes, Hypertension
Background: Chronic kidney disease (CKD) is a silent epidemic. The true prevalence of CKD with in a population are very difficult to estimate, since early to moderate CKD were usually asymptomatic. ESRD in the consequence of CKD is one of the most expensive diseases to treat.Only way is to prevent it and Hence this was conducted to estimate the prevalence of CKD and its associated risk factors among adults in selected slums of Chennai.
Methods: This is a cross sectional study done from May 2013 to June 2014 in selected slums of Chennai. The study population includes adult males and females. Multi stage sampling method used. Sample size covered was 400. A semi structured questionnaire used as tool. Based on the serum creatinine eGFR calculated using modified MDRD study equation and CKD prevalence was identified. The data was entered in MS excel and analyzed using SPSS version 21.
Results: Total of 400 participants involved. Females were predominant in the study. Among them, 67 (16.8%) were diagnosed as CKD patients and Stage 1, 4.0% had stage 2, 3.6% had stage 3, 1.3% had stage 4 and 0.5% had stage 5 at the time of diagnosis.
Conclusions: This study revealed prevalence of CKD among slum population was 16.8%. This study showed that old age, uncontrolled hypertension, uneducated, Diabetes with poor control, overuse of analgesics, H/o smoking, obesity, alcoholism, passive smoking, family H/o CKD and proteinuria were significant risk factor for CKD among study subjects. Slum population with risk factors should be regularly screened for CKD.
Prabahar MR, Chandrasekaran V, Soundararajan P. Epidemic of chronic kidney disease in India-what can be done? Saudi J Kidney Dis Transplant. 2008;19(5):847.
Rajapurkar MM, John GT, Kirpalani AL, Abraham G, Agarwal SK, Almeida AF, et al. What do we know about chronic kidney disease in India: first report of the Indian CKD registry. BMC Nephrol. 2012;13(1):10.
Singh AK, Farag YM, Mittal BV, Subramanian KK, Reddy SR, Acharya VN, et al. Epidemiology and risk factors of chronic kidney disease in India-results from the SEEK (Screening and Early Evaluation of Kidney Disease) study. BMC Nephrol. 2013;14(1):114.
Price CP, Finney H. Developments in the assessment of glomerular filtration rate. Clin Chim Acta Int J Clin Chem. 2000;297(1-2):55–66.
Lamb EJ, O’Riordan SE, Delaney MP. Kidney function in older people: pathology, assessment and management. Clin Chim Acta Int J Clin Chem. 2003;334(1-2):25–40.
Varma PP, Raman DK, Ramakrishnan TS, Singh P, Varma A. Prevalence of early stages of chronic kidney disease in apparently healthy central government employees in India. Nephrol Dial Transplant. 2010;25(9):3011–7.
Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third national health and nutrition examination survey. Am J Kidney Dis. 2003;41(1):1–12.
Singh NP, Ingle GK, Saini VK, Jami A, Beniwal P, Lal M, et al. Prevalence of low glomerular filtration rate, proteinuria and associated risk factors in North India using Cockcroft-Gault and Modification of Diet in Renal Disease equation: an observational, cross-sectional study. BMC Nephrol. 2009;10(1):4.
Mani MK. Prevention of chronic renal failure at the community level. Kidney Int. 2003;63:S86–S89.
Ejerblad E. Obesity and Risk for Chronic Renal Failure. J Am Soc Nephrol. 2006;17(6):1695–702.
Salve H, Mahajan S, Misra P. Prevalence of chronic kidney diseases and its determinants among perimenopausal women in a rural area of North India: A community-based study. Indian J Nephrol. 2012;22(6):438–43.