Clinical laboratory strategies for managing pandemic outbreaks
DOI:
https://doi.org/10.18203/2394-6040.ijcmph20240645Keywords:
Pandemic, Preparedness, Response, Management, LaboratoryAbstract
This review article comprehensively examines clinical laboratory strategies for managing pandemic outbreaks, with a particular focus on lessons learned from the COVID-19 pandemic. Drawing upon an extensive analysis of existing literature from databases such as PubMed, Web of Science, and Cochrane, as well as manual searches on Google Scholar, the study aims to provide insights into key aspects of pandemic preparedness and response. The literature review encompasses diverse combinations of medical terminology, emphasizing the role and response of clinical laboratories during pandemics. The primary focus areas include rapid test development and deployment, increased testing capacity, sample collection, and transportation protocols, data management, personnel safety, resource allocation, adaptability, and quality control measures. The inclusion of articles in this study adheres to rigorous criteria, ensuring a thorough and robust review process. The findings highlight the critical importance of rapid and accurate diagnostic testing, especially in the early stages of a pandemic, to facilitate timely interventions and containment. Efficient sample collection and transportation systems are crucial for maintaining the integrity of specimens, while advanced data management and reporting systems contribute to informed decision-making. Adaptability and flexibility are identified as indispensable traits for navigating the dynamic challenges of a pandemic, and stringent quality control measures are foundational for upholding the accuracy of diagnostic testing. The review underscores the collaborative efforts needed among clinical laboratories, public health agencies, and research institutions to strengthen global pandemic preparedness and response strategies.
References
Organization WH. The true death toll of COVID 19. 2023. Avaiable at: https://www.who.int/data/stories/ the-true-death-toll-of-covid-19-estimating-global-excess-mortality. Accessed on 10 January 2024.
Tulenko K, Vervoort D. Cracks in the system: the effects of the coronavirus pandemic on public health systems. Am Rev Publ Administration. 2020;50(6-7):455-66.
Godshall CE, Banach DB. Pandemic preparedness. Infect Disease Clin. 2021;35(4):1077-89.
Moynihan R, Sanders S, Michaleff ZA, Scott AM, Clark J, To EJ, et al. Pandemic impacts on healthcare utilisation: a systematic review. MedRxiv. 2020;2020.
Tandara L, Filipi P, Supe Domic D, Branka K, Ivo I, Sanda SS, et al. Laboratory medicine in pandemic of COVID-19. Biochemia Medica. 2022;32(2):168-81.
Adeli K. Critical role of laboratory medicine in the global response to the COVID-19 pandemic. Clin Chemistr Lab Med. 2020;58(7):1019-20.
Pecora ND, Pettengill MA. The Role of Laboratory-Based Viral Testing in the COVID-19 Pandemic. Clin Chemistr. 2021;68(1):33-5.
Duś-Ilnicka I, Szymczak A, Małodobra-Mazur M, Tokarski M. Role of laboratory medicine in SARS-CoV-2 diagnostics. Lessons learned from a pandemic. Healthcare. 2021;9(7):915.
Uchejeso OM, Rinpan JI, Chongs ME, Ekpere-Ezeugwu MO. Fighting COVID-19: The Medical Laboratory Involvement. Fighting the COVID-19 Pandemic. 2021;301.
Sahajpal NS, Mondal AK, Ananth S, Allan N, Sadanand F, Pankaj A, et al. Making a Difference: Adaptation of the Clinical Laboratory in Response to the Rapidly Evolving COVID-19 Pandemic. Academic Pathol. 2021;8:23742895211023948.
Alzeyara F. Laboratories preparedness in response to COVID-19 pandemic in qatar strategic planning and emergency supply chain management. 2022.
Mfuh KO, Abanda NN, Titanji BK. Strengthening diagnostic capacity in Africa as a key pillar of public health and pandemic preparedness. PLOS Global Publ Heal. 2023;3(6):e0001998.
Rakeman-Cagno JL, Persing DH, Loeffelholz MJ. Maintaining point of care testing capacity and pandemic preparedness in the post-COVID-19 era. Expert Rev Molecular Diagnostics. 2023;1-5.
Cornish NE, Anderson NL, Arambula DG, Matthew JA, Andrew B, Nancy CB, et al. Clinical Laboratory Biosafety Gaps: Lessons Learned from Past Outbreaks Reveal a Path to a Safer Future. Clin Microbiol Rev. 2021;34(3):10.1128/cmr.00126-00118.
Oliveira FNd, Eckhardt D, Leiras A, Paulo G, Irineu de BJ, Hugo TYY, et al. Toward the development of a Preparedness and Response Protocol for epidemics and pandemics. Production. 2023;33:e20220034.
Lal A, Ashworth HC, Dada S, Hoemeke L, Tambo E. Optimizing pandemic preparedness and response through health information systems: lessons learned from Ebola to COVID-19. Disaster medicine and public health preparedness. 2022;16(1):333-40.
Butt ZA. Big data and artificial intelligence for pandemic preparedness. In: Artificial Intelligence, Big Data, Blockchain and 5G for the Digital Transformation of the Healthcare Industry. Elsevier. 2024;403-18.
David R, Richard A, Connellan C, Katharina L, Chiusano M, Carole G, et al. Umbrella Data Management Plans to integrate FAIR data: lessons from the ISIDORe and BY-COVID consortia for pandemic preparedness. CODATA Data Science J. 2023;22(35):1-15.
Stöcker A, Demirer I, Gunkel S. Stockpiled personal protective equipment and knowledge of pandemic plans as predictors of perceived pandemic preparedness among German general practitioners. Plos one. 2021;16(8):e0255986.
Martínez MJ, Cotten M, Phan MVT, Karsten B, Mateu E, Truls ML, et al. Viral epidemic preparedness: a perspective from five clinical microbiology laboratories in Europe. Clin Microbiol Infect. 2023.
Dewar B, Anderson JE, Kwok ES. Physician preparedness for resource allocation decisions under pandemic conditions: a cross-sectional survey of Canadian physicians, April 2020. PloS One. 2020;15(10):e0238842.
Romney D, Fox H, Carlson S, Bachmann D, O’Mathuna D, Kman N. Allocation of scarce resources in a pandemic: a systematic review of US state crisis standards of care documents. Disaster medicine and public health preparedness. 2020;14(5):677-83.
Prieto J, Gomez J. Multi-objective risk-based resource allocation for urban pandemic preparedness: The covid-19 case in bogotá, colombia. medRxiv. 2021;2021.
Torreele E, Wolfe D, Kazatchkine M, Amadou S, Kiat R, Joseph RAF, et al. From private incentives to public health need: rethinking research and development for pandemic preparedness. Lancet Global Health. 2023;11(10):e1658-666.
Newland M, Durham D, Asher J, John JT, Jonathan S, Ruben OD, et al. Improving pandemic preparedness through better, faster influenza vaccines. Expert Rev Vaccines. 2021;20(3):235-42.
Mirtsch M, Koch C, Ashari PA, Blind K, Castka P. Quality assurance in supply chains during the COVID-19 pandemic: empirical evidence on organisational resilience of conformity assessment bodies. Total Quality Management Business Excellence. 2023;34(5-6):615-36.
Pawar SD, Kode SS, Keng SS, Tare DS, Abraham P. Steps, implementation and importance of quality management in diagnostic laboratories with special emphasis on coronavirus disease-2019. Indian J Med Microbiol. 2020;38(3-4):243-51.
Sundararaman T. Health systems preparedness for COVID-19 pandemic. Indian J Publ Heal. 2020;64(6):91.
